Direct screening of a dynamic combinatorial library using mass spectrometry
نویسندگان
چکیده
منابع مشابه
Direct screening of a dynamic combinatorial library using mass spectrometry.
A dynamic combinatorial library (DCL) screening approach is described that permits direct identification of the effective (from ineffective) combination of building blocks in the equilibrating DCL. The approach uses Fourier transform ion cyclotron resonance mass spectrometry (FTICR MS) together with sustained off-resonance irradiation collision activated dissociation (SORI-CAD) to detect noncov...
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ژورنال
عنوان ژورنال: Journal of the American Society for Mass Spectrometry
سال: 2006
ISSN: 1044-0305,1879-1123
DOI: 10.1016/j.jasms.2006.03.017